Physiome Project

The term "physiome" comes from "physio" (life) + "ome" (as a whole), and is intended to provide a "quantitative description of physiological dynamics and functional behaviour of the intact organism".

The Physiome Project develops a multi-scale modelling framework for understanding physiological function that allows models to be combined and linked in a hierarchical fashion.

CellML and FieldML formats are used to store and exchange computer-based mathematical models in a reproducible and reusable manner.

All software tools (including APIs, authoring tools, visualization tools, graphical user interfaces, and simulation tools) developed for the Physiome Project are open source, using commercially friendly licenses (a commercial package, for example, can link the open-source libraries).

In partnership with the Disease Maps Project, the Physiome Project aims to explore the modular approach for building disease models and investigate how CellML and SBGN formats can interoperate efficiently. The acute kidney injury project is chosen as the pilot one: an agreement on collaboration is reached with the AKIPREV leaders.

	Peter Hunter, MNZM, DPhil Oxf, ME, FRSNZ FRS University of Auckland, Auckland, New Zealand Director of the Auckland Bioengineering Institute, Professor of Engineering Science at the University of Auckland, Director of the Medical Technologies Centre of Research Excellence
	David Nickerson, PhD, ME, BE University of Auckland, Auckland, New Zealand Aotearoa Physiome Fellow, Leader of the Auckland Renal Physiome project, an elected member of the CellML and SED-ML editorial boards, a COMBINE coordinator