Disease maps for specific diseases
Cross-disease projects
Adverse outcome maps for immunotoxicology
The Disease Maps Community consolidates efforts focused on describing disease mechanisms. We aim to progress together through advancing technological solutions, sharing resources and best practices. New contributors are very welcome: please propose a new disease map or join one of the existing projects. Project progress status:
☆☆☆☆☆ Initiated/funded ★☆☆☆☆ Active development ★★☆☆☆ Available for exploration online |
★★★☆☆ Published ★★★★☆ Maintained and improved ★★★★★ Applications demonstrated |
This section lists projects focused on specific diseases. The list is organised according to the progress status of the projects.
COVID-19, Parkinson’s disease, cancer, rheumatoid arthritis, asthma, sarcopenia, cystic fibrosis, heart failure, atherosclerosis, osteoarthritis, Sjogren’s syndrome, diabetic kidney disease, atopic dermatitis, psoriasis, liver steatosis, cholestasis
Resource: COVID-19 Disease Map Contact: Marek Ostaszewski, University of Luxembourg, Belvaux, Luxembourg Publications: PubMed |
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Resource: Parkinson's Disease Map Contact: Marek Ostaszewski, University of Luxembourg, Belvaux, Luxembourg Publications: PubMed |
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Resource: Atlas of Cancer Signalling Network Contact: Inna Kuperstein, Institut Curie, Paris, France Publications: PubMed |
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Resource: Rheumatoid Arthritis Map Contact: Anna Niarakis, Paul Sabatier University - Toulouse III, Toulouse, France Publications: DOI |
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Resource: AsthmaMap Contact: Alexander Mazein, University of Luxembourg, Belvaux, Luxembourg Publications: PubMed |
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Resource: Sarcopenia Map Contact: Matti Hoch, University of Rostock, Rostock, Germany Publications: PubMed |
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Resource: CyFi-MAP Contact: Catarina Pereira, University of Lisbon, Lisbon, Portugal Publications: PubMed |
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Resource: CardioMap Contact: Nikolaus Berndt, Charité – Universitätsmedizin Berlin; Irina Balaur, University of Luxembourg | Publications: PubMed |
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Resource: Atherosclerosis Map Contact: Steven Watterson, Ulster University, Derry, Northern Ireland, UK Publications: PubMed | Model: BioModels |
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Resource: Liver Lipid Metabolism Physiological Map Contact: Luiz Ladeira, University of Liège, Liège, Belgium Publications: Preprint |
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Resource: Liver Bile Secretion Physiological Map Contact: Luiz Ladeira, University of Liège, Liège, Belgium Publications: Preprint |
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Resource: KneePainMap Contact: Bernd Seilheimer, Heel GmbH, Germany |
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Resource: Sjogren Map Contact: Sacha E Silva-Saffar, University of Evry, University of Paris-Saclay, France |
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Resource: Diabetic Kidney Disease Map Contact: Farnoush Kiyanpour, Isfahan University of Medical Sciences, Iran |
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Resource: Atopic Dermatitis Map Contact: Marcio Luis Acencio, University of Luxembourg, Belvaux, Luxembourg |
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Resource: Psoriasis Map Contact: Marcio Luis Acencio, University of Luxembourg, Belvaux, Luxembourg |
This section includes projects that focus on shared mechanisms of two or more diseases, interactions between two or more diseases, or broader aspects applicable to many diseases.
Resource: Atlas of Inflammation Resolution Contact: Matti Hoch, University of Rostock, Rostock, Germany Publications: PubMed |
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Resource: Neural Tube Closure Physiological Map Contact: Alessio Gamba, University of Liège, Liège, Belgium Publications: PubMed |
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Resource: SYSCID Map Diseases: IBD, rheumatoid arthritis and systemic lupus erythematosus Contact: Marcio Luis Acencio, University of Luxembourg, Belvaux, Luxembourg Publications: DOI |
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Resource: ImmUniverse Map Diseases: ulcerative colitis, atopic dermatitis Contact: Marcio Luis Acencio, University of Luxembourg, Belvaux, Luxembourg |
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Resource: Nephron Physiological Map Diseases: kidney crystallopathy, tubular necrosis Contact: Alessio Gamba, University of Liège, Liège, Belgium |
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Resource: Brain Development Physiological Map Contact: Luiz Ladeira, University of Liège, Liège, Belgium |
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Resource: Human Immune System Development Map (HIDmap) Contact: Christiane Spruck, IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany |
This section includes maps that describe mechanisms of adverse effects of various treatments and are based on the adverse outcome pathway (AOP) concept in toxicology.
Resource: CAR T cell AOP Map Contact: Alexander Mazein, University of Luxembourg, Belvaux, Luxembourg Publications: Preprint |
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Resource: Cytokine Release Syndrome Map Contact: Alexander Mazein, University of Luxembourg, Belvaux, Luxembourg |